Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to soil macroorganisms except arthropods

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

LC50 > 1,000 mg/kg for Eisenia fetida based on read across (OECD 207) 

Key value for chemical safety assessment

Additional information

The assessment of the terrestrial toxicity should be based on the outcome of aquatic toxicity testing. Pursuant to ECHA decision on a compliance check CCH-D-2114517125-59-01/F new studies with the registered substance will be conducted in the future. The finalised studies will be reported in an updated dossier and the hazard assessment will be re-evaluated accordingly. Thus, the strategy of terrestrial toxicity will be evaluated later when all aquatic toxicity studies are available.

There are no adequate study data on terrestrial organisms of the registration substance available. The assessment was therefore based on studies conducted with the analogue substance 1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters (CAS No. 90218-76-1) as part of a read across approach, which is in accordance with Regulation (EC) No. 1907/2006. Annex XI, 1.5. For each specific endpoint the source substance(s) structurally closest to the target substance is/are chosen for read-across, with due regard to the requirements of adequacy of the available data. Structural similarities and similarities in properties and/or activities of the source and target substance are the basis of read-across. A detailed justification is provided in the technical dossier (see IUCLID Section 13). Please consider that the originally proposed category approach addressing all Polyfunctional acid esters (PFAE) aromatic is currently under revision and will finally result in an analogue approach for the registration. Therefore, two documents, the category justification and explanatory notes for the analogue approach are provided in Section 13.

The study with 1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters (CAS No. 90218-76-1) was performed under GLP and according to EU method C.8 using the earthworm Eisenia foetida as test organism. This limit test performed at a concentration of 1,000 mg/kg dry soil was conducted using artificial soil. No mortality was observed in the control and the treatment during the test period of 14 days. Hence, the 14 d-LC 50 is determined to be > 1,000 mg/kg dry soil.

Thus, based on the above mentioned results, and due to the structural similarities and a consistent ecotoxicological/environmental fate profile of the substances, it can be concluded that no acute toxicity of 1,2,4-Benzenetricarboxylic acid, tri-C9-11-alkyl esters (CAS No. 94279-36-4) to soil macroorganisms is expected.