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EC number: 304-780-6
CAS number: 94279-36-4
No toxic effects up to the limit of water solubility (< 0.05 mg/L) for Brachydanio rerio based on read across (OECD 203)
As no valid study is available for assessing the acute toxicity to fish
of 1,2,4-Benzenetricarboxylic acid, tri-C9-11-alkyl esters (CAS No.
94279-36-4), in accordance to Regulation (EC) No. 1907/2006 Annex XI,
1.5 Grouping of substances, a read-across to the structurally related
category member 1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl
triesters (CAS No. 90218-76-1) was conducted. The read across is
justified due to a) the structural similarity of the category members
and b) similar physico-chemical properties resulting in a similar
environmental fate and ecotoxicity profile. Further justification is
given within the endpoint summary 6.1 and within the category
justification section 13.
The study with 1,2,4-Benzenetricarboxylic acid, decyl octyl ester (CAS
No. 90218-76-1) was performed under semi-static conditions according to
GLP and EU method C.1 using Brachydanio rerio as test organism (Scholz,
1994). In this limit test, no mortality was observed and a LC50 (96 h) >
4.1 mg/L (measured, WAF) was determined, which corresponds to the
highest water solubility of the substance under test conditions.
Thus, based on the above mentioned results, and due to the structural
similarities and a consistent ecotoxicological/environmental fate
profile of the substances, as are explained with in the overall endpoint
summary in IUCLID chapter 6.1, it can be concluded that no acute
toxicity to fish is expected for 1,2,4-Benzenetricarboxylic acid,
tri-C9-11-alkyl esters (CAS No. CAS No. 94279-36-4) to fish is very low.
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