Registration Dossier
Registration Dossier
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EC number: 201-148-0 | CAS number: 78-83-1
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
Data source
Reference
- Reference Type:
- secondary source
- Title:
- No information
- Author:
- Dillingham E.O. et al.
- Year:
- 1 973
- Bibliographic source:
- J. Pharmaceut. Sci., 62, 22-30, (1973); cited in BG Chemie (ed.): 2-Methylpropanol-1, in:|Toxicological Evaluations 1 - Potential Health Hazards of Existing Chemicals, Springer Verlag, Berlin, pp. 43-57, (1990)
Materials and methods
- Principles of method if other than guideline:
- The test substance was applied i.p. to mice to determine the LC50.
- GLP compliance:
- no
Test material
- Reference substance name:
- 2-methylpropan-1-ol
- EC Number:
- 201-148-0
- EC Name:
- 2-methylpropan-1-ol
- Cas Number:
- 78-83-1
- Molecular formula:
- C4H10O
- IUPAC Name:
- 2-methylpropan-1-ol
Constituent 1
- Specific details on test material used for the study:
- Isobutanol
Test animals
- Species:
- mouse
- Strain:
- ICR
- Sex:
- male
Administration / exposure
- Route of administration:
- intraperitoneal
- Doses:
- no data
- No. of animals per sex per dose:
- no data
- Details on study design:
- - Duration of observation period following administration: 7 days
Results and discussion
Effect levels
- Key result
- Sex:
- male
- Dose descriptor:
- LD50
- Effect level:
- 312 mg/kg bw
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
