Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
additional toxicological information
Type of information:
other: review
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature

Data source

Reference
Reference Type:
secondary source
Title:
Hoehere Alkohole und Aethanolwirkung beim Menschen
Author:
Prokop L. and Machata G.
Year:
1974
Bibliographic source:
Blutalkohol, 11, 80-87, 1974

Materials and methods

Type of study / information:
Review on narcotic effects etc.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2-methylpropan-1-ol
EC Number:
201-148-0
EC Name:
2-methylpropan-1-ol
Cas Number:
78-83-1
Molecular formula:
C4H10O
IUPAC Name:
2-methylpropan-1-ol

Results and discussion

Any other information on results incl. tables

Isobutanol has a stronger narcotic effects than ethanol (factor 11.7)

further information about behaviour and personal comfort in a drinking study were irrelevant since mixtures of alcohls were tested (isobutanol was groupped with other alcohols as rotgut)

Applicant's summary and conclusion