Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
additional toxicological information
Type of information:
other: review
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature

Data source

Reference
Reference Type:
secondary source
Title:
Hoehere Alkohole und Aethanolwirkung beim Menschen
Author:
Prokop L. and Machata G.
Year:
1974
Bibliographic source:
Blutalkohol, 11, 80-87, 1974

Materials and methods

Type of study / information:
Review on narcotic effects etc.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2-methylpropan-1-ol
EC Number:
201-148-0
EC Name:
2-methylpropan-1-ol
Cas Number:
78-83-1
Molecular formula:
C4H10O
IUPAC Name:
2-methylpropan-1-ol

Results and discussion

Any other information on results incl. tables

Isobutanol has a stronger narcotic effects than ethanol (factor 11.7)

further information about behaviour and personal comfort in a drinking study were irrelevant since mixtures of alcohls were tested (isobutanol was groupped with other alcohols as rotgut)

Applicant's summary and conclusion