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EC number: 201-148-0
CAS number: 78-83-1
Acute tests on all three trophic levels were
performed to examine the aquatic toxicity of iso-butanol.
Daphnia turned out to be the most sensitive
species revealing an EC50 (48h) of 1100 mg/L. Effects of iso-butanol
towards fish, daphnia, and algae were found in the same range providing
a LC50 (96h) of 1430 mg/L for fish and an EC50 (72h) of 1799 mg/L for
Thus, iso-butanol is considered with high
probability acutely not harmful to aquatic organisms. No adverse effects have
To determine the
long-term toxicity, a study on the reproduction of Daphnia magna was
performed. The calculated NOEC (21d) in this study was 20 mg/L [Kuehn &
al., 1989]. No
data on long-term toxicity on fish are available. The hazard assessment
of iso-butanol reveals neither a need to classify the substance as
dangerous for the environment, nor is it a PBT or vPvB substance.
Therefore, and for reasons of animal welfare, a long-term toxicity study
in fish is not provided.
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