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EC number: 283-294-5
CAS number: 84604-16-0
Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Saccharomyces cerevisiae, Saccharomycelaceae.
The test substance is a complex mixture of organic components in water.
Each component will have its own partition coefficient. Therefore the
partition coefficient of the test substance cannot be determined.
Due to the complex composition of the substance “Saccharomyces
cerevisiae extract”, it is not feasible to determine its partition
coefficient experimentally. The shake flask method, the HPLC method and
the slowstirring method are not applicable to this substance. QSARs
calculations are not possible due to the complex composition and the
unknown precise structure of the constituents. Even the estimation of
log Kow based on the solubility in water and in n-octanol is technically
not feasible. A rough estimated single log Kow value or a broad range of
log Kow values for “Saccharomyces cerevisiae extract” would not
contribute to hazard assessment or to classification. Indeed, the
constituents of this soluble fraction are very different substances with
different physical-chemical properties and probably the log Kow value of
the organic constituents will cover a broad range of log Kow values.
However due to the high solubility of these components (20% at 50°C pH 5
to 5.5), the log Kow must be low, and therefore it is concluded that
there is no concern on bioaccumulation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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