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EC number: 283-294-5
CAS number: 84604-16-0
Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Saccharomyces cerevisiae, Saccharomycelaceae.
Only an acute toxicity study with algae is available in which the yeast
extract did not show any toxicity. Moreover, acute toxicity to fish and
to aquatic invertebrates from S. cerevisiae Lysate dossier are available
and show no toxicity. According to the read-across assessment, no
toxicity of S. cerevisiae extract is expected in the aquatic
compartment. Yeast, yeast extracts and yeast cell wall fractions have
widely been fed to poultry, cattle and other livestock. In addition,
many animals in ecotoxicity studies are fed or supplemented with yeast
or yeast extracts. Yeast S. cerevisiae is one of the most widely used
microorganisms as a DFM (Direct-Fed Microbials) in livestock operations.
Finally, the The OECD guidelines for the testing of chemicals (OECD
series on testing and assessment Number 55/ ENV/JM/MONO(2006)22) refer
to the feeding of the aquacultures with yeast, following protocols for
sediment toxicity and bioaccumulation test, such as US EPA (report
600/R-99/064 of March 2000).
To conlude, testing to evaluate long-term toxicity to aquatic
invertebrates is not considered scientifically necessary and no toxicity
of S. cerevisiae to aquatic compartments is expected .
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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