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EC number: 206-581-9
CAS number: 355-37-3
Table 2. Experimental Results
Dose (mg/Kg) and Mortality
a key acute oral toxicity study, the test material
(1,1,1,2,2,3,3,4,4,5,5,6,6-tridecafluorohexane) was administered via
oral gavage at single doses of 50, 500, or 5000 mg/Kg to male and female
ddY mice (10/sex/dose).
were observed frequently on the day of dosing and thereafter once daily
for general conditions, behaviour, and signs of toxicity for 7 days post
exposure. At the end of the observation period, all surviving animals
were sacrificed under ether anaesthesia and necropsied for gross
mortality was observed through the study period. No adverse effects of
treatment were observed in animals of either sex exposed to the test
material at doses of 50, 500, or 5000 mg/Kg.
on the results observed in the study, the acute oral LD50 of
1,1,1,2,2,3,3,4,4,5,5,6,6-tridecafluorohexane was determined to be >5000
mg/Kg in the mouse.
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