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EC number: 206-581-9
CAS number: 355-37-3
Table 1. Exposure Concentration in the Chamber
Measured Concentration (ppm) by time (hours)
Table 2. Environment in the Chamber
Time after commencement of exposure (hours)
Relative Humidity (%)
Table 3. Body Weight Results (grams)
Day After Exposure
a key acute inhalation toxicity study, the test material
(1,1,1,2,2,3,3,4,4,5,5,6,6-tridecafluorohexane) was administered via
whole body inhalation (vapour) to male and female SD (Crj:CD, SPF) rats
(5/ex/concentration) at a concentration of 10000 ppm (measured
concentration was 11,100 ppm) for a period of 4 hours.
the commencement of exposure to 2 hours after the end of the exposure,
all rats were observed for clinical signs every hour, and once a day
thereafter for a period of 14 days. All rats were weighed just before 3,
7, & 14 days post exposure. At the end of the 14-day observation period,
animals were euthanized by severing the abdominal aorta under thiopental
sodium anaesthesia and then subjected to necropsy.
mortality was observed through the study period and no clinical signs of
test-material related toxicity were observed in animals of either sex.
Normal increase in body weight was observed in all male and female rats
to the end of the observation period and necropsy did not reveal any
on the results observed in this study, the minimal lethal concentration
(LCL0) of 1,1,1,2,2,3,3,4,4,5,5,6,6-tridecafluorohexane was
determined to be >11,100 ppm.
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