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Reliable short-term toxicity tests results are available for freshwater fish (Brachydanio rerio), invertebrates (Daphnia magna) and algae (Scenedesmus subspicatus). LC50 or EC50 values for the three organisms were 80, 21.2 or 140 (two different studies), and >819 mg/L respectively. A NOEC of 237 mg/L was determined in the algal test.

A 21-day NOEC of ≥100 mg/L has been determined for the effects of the test substance on mortality and reproduction of Daphnia magna. The result has been reinterpreted by the reviewer in terms of the mean measured concentration of the test substance to give a NOEC of ≥66 mg/L.

The apparent inconsistency in the results of the short- and long-term tests with Daphnia magna might be explained by the flat dose response in the short-term test. As a consequence it is possible that the 48-h EC50 value could be closer to 100 mg/L than is indicated by the value determined by linear regression. The results of the second short-term test with D. magna (48-h EC50: 140 mg/L and NOEC: 100 mg/L) are consistent with this thesis.

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