Registration Dossier

Classification & Labelling & PBT assessment

PBT assessment

Currently viewing:

Administrative data

PBT assessment: overall result

PBT status:
the substance is not PBT / vPvB

PACM is poorly degraded in water, based upon a weight of evidence regarding biodegradability. The substance is not readily biodegradable, and was shown to be poorly eliminated in an inherent biodegradability test. Therefore, no conclusions may be drawn with respect to the P/vP properties of the substance.

The substance is "not B/vB" based on an experimentally determined octanol-water partitioning coefficient of log Kow = 2.03 for the substance, and an experimentally-derived BCF of < 60 for the structurally similar substance DMDC (CAS 6864 -37 -5).

With respect to aquatic toxicity, the substance is "not T " since the lowest available chronic value is > 0.01 mg/L. Experimental chronic toxicity data are available for invertebrates and algae, for which the chronic values are greater than 0.01 mg/L. For fish, the NOEC was estimated to be greater than 1 mg/L (ACR approach). With respect to mammalian toxicity, the substance is "T", based on the self-classification as STOT-RE, target organs: skeletal muscle and liver, for vacuolar degeneration identified by histopathology. Therefore, with respect to all endpoints, the substance is "T".

In summary, the substance can be regarded as not PBT and not vPvB.

Likely routes of exposure:

Dermal, inhalation