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Toxicological information

Sensitisation data (human)

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Administrative data

Endpoint:
sensitisation data (humans)
Type of information:
other: case report
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: This is case report of adverse effects in an occupational setting. It is reliable with restrictions that no cause and effect can be proven with this information. The authors may have designed the study with the intention of showing adverse effects.

Data source

Reference
Reference Type:
publication
Title:
An experimental study of scleroderma-like disease by epoxy resin and methylchloroform.
Author:
Matsushita T, Aoyama K, Nomura S, et.al,
Year:
1980
Bibliographic source:
Jap. J. Ind. Med. 22: 614.

Materials and methods

Type of sensitisation studied:
skin
Study type:
case report
Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
Case report. No guideline available.
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Results of examinations:
sensitising

Any other information on results incl. tables

The substance applied was not a pure substance, and so it is possible that another chemical was responsible for the outcome.

Applicant's summary and conclusion

Conclusions:
The authors of this study conclude that 4,4'-methylenedicyclohexanamine is a dermal sensitiser.