Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 446-990-1 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Two ready biodegradation studies (OECD 301D) have been performed on the registered substance (active substance: in a solid state). In these studies, a total of 35% and 45% degradation were reached respectively. These results correspond well with a predicted total mineralisation of the xylitol and anhydro-xylitol fractions. Nevertheless, employing the low inoculum concentration required to meet OECD 301D guideline recommendations, the bacteria may not have had the time to adapt to the larger constituents of the mixture during the timeframe of this study. From the previous information and the BIOWIN prediction of biodegradation of the different components of the registered substance, we would expect Xylitol, anhydro-xylitol and xylityl monoglucoside to be biodegraded in a ready test, at least when tested individually. It is recognised that "mixtures" containing a homologous series of constituents may take longer to biodegrade than single substances (as mentioned in the decision scheme of the CLP guidance (20135)). This is due to the increased lag time as the competent degraders move from one available food source to another. Then two additional ready biodegradability tests were performed with the registered substance in water (corresponding to the commercial product); this corresponds to the physical state (liquid form) in which the substance will end up in the environment. In the first assay, the batch tested (83.97% dry matter) reached 69-73% in 28 days (10 day window reached) according to the OECD test n° 301F.
In the second assay (performed according to OECD test n° 301D), the commercial product reached 65 and 63% biodegradation with two types of inoculum (sludge from STP and river water, respectively) in 28 days and 68% biodegradation in 60 days (with river water as inoculum). As the registered substance is a multi-constituent substance in homologous series, the 10 days-window does not need to be satisfied to be "readily biodegradable" (guidance on the application of the CLP criteria, version 5.0: II.2.1.2, page 564). So the registered substance is considered "readily biodegradable".
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
