Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 446-990-1
CAS number: -
Maximum concentration not causing irritating effects in preliminary test: 100 %
Signs of irritation during induction:
Application of sodium laurylsulfate at 10 % at day 7
Evidence of sensitisation of each challenge concentration:
After induction (intradermic injection and topical application) of 21
Guinea Pigs (female) of treated group with the pure test product
LCA01006 and a 17 days rest phase, the challenge phase, under occlusive
dressing for 24 hours, consisted to a single topical application of the
test product at 100% and diluted at 50%, according to the experimental
protocol established from the O.E.C.D. guideline n°406 dated July
17th,1992 and the method B.6 of the directive 92/69/EEC dated December
No macroscopic cutaneous reactions attributable to allergy was recorded
during the examination following the removal of the occlusive dressing
(challenge phase) from the animals of the treated group with the test
No cutaneous intolerance reaction was recorded in animals from the
negative control group.
In conclusion, in view of these results, under these experimental
conditions, the product LCA01006, in accordance with the criteria for
classification, packaging and labelling of dangerous substances of the
E.E.C. Directives 67/548 and 93/21, must not be classified.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again