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Toxicological information

Additional toxicological data

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Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Special test procedure.

Data source

Reference
Reference Type:
publication
Title:
Toxicological and Pharmacological Actions of Methacrylate.
Author:
Mir GN, Lawrence WH, Autian J
Year:
1974
Bibliographic source:
J. Pharm. Sci. 63: 376 - 381

Materials and methods

Type of study / information:
other: Heart/Blood-circulation
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Any other information on results incl. tables

abrupt fall followed by a secondary rise in blood pressure, increased respiratory rate, decreased heart rate and electrocardiographic changes.
                 LD = 0.1 g/kg
                    = 100 mg/kg

Applicant's summary and conclusion