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EC number: 201-204-4
CAS number: 79-41-4
SUMMARY OF MAA CHAMBER CONCENTRATIONS
AND ASSOCIATED RAT MORTALITY
(# DEATHS/# EXPOSED)
21 / 79
3.4 +/- 0.17
0.91 +/- 0.26
0 / 5
37 / 63
3.7 +/- 0.24
2.2 +/- 0.94
1 / 5
50 / 50
3.7 +/- 0.27
3.6 +/- 0.41
2 / 5
57 / 43
3.6 +/- 0.20
4.7 +/- 1.8
5 / 5
* Aerosol/vapor ratios were calculated
using the mean aerosol and vapor concentrations for each exposure.
Aerosol mass median diameters were 10, 6.5, 5.5, or 7.2 um for
concentrations of 4.3, 5.9, 7.3, 8.2 mg/L, respectively.
Rats (5m/5f) were exposed to a vapour/aerosol mix at four doses between
4.3 and 8.2 mg/L (1201 - 2291 ppm).
Mortality is clearly associated with exposure to aerosol. Exposure to
(saturated) vapour was +/- the same at all concentration levels (3.4-3.7
mg/L). Exposure to vapour alone was not associated with mortality, while
exposure to aerosol increased ( 0.9-4.7 mg/L) in parallel to an increase
Using a valid experimental method, the 4 hour LC50 of MAA to male and
female rats was 7.1 mg/L air (vapour/aerosol mix).
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