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EC number: 203-308-5
CAS number: 105-55-5
It's a range finding test for carcinogenicity test. In order to
establish the maximum tolerated concentrations of DETU for
administration to dosed animals in the chronic studies, subchronic
toxicity tests were conducted. Rats were exposed to DETU in diet during
seven weeks to 147, 215, 316 and 464 ppm.
- At 316 ppm concentration: Mean body weight gain increased by 3 % among
male rats compared to control group while it decreased by 11% in female
rats. 1 female rat died and another had an arched back and rough coat.
- At 215 ppm concentration: Mean body weight gain decreased by 10 %
among male rats compared to control group while it decreased by 1% in
=> The maximum tolerated concentration was around 250 ppm.
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