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EC number: 203-308-5
CAS number: 105-55-5
The determination of the growth inhibition of the freshwater algae Pseudokirchneriella subcapitata exposed to the test item 1,3 – Diethyl-2-thiourea for a duration of 72 hours was assessed according to the OECD Guideline 201 and GLP requirements. ErC50 was determined: ErC50-72h=310 mg/L
The determination of the growth
inhibition of the freshwater algae Pseudokirchneriella subcapitata (previously
known as Raphidocelis subcapitata and Selenastrum capricornutum)
exposed to the test item 1,3 – Diethyl-2-thiourea for a duration of 72
hours was assessed according to the OECD Guideline 201.
Algae were exposed to 500 to 50 mg/L
1,3 – Diethyl-2-thiourea dissolved in dilution water. The toxic effect
measured during the assay was the inhibition of cellular multiplication
over a time period of 72 hours.
The concentrations of test item
causing a 50 % reduction in biomass (EbC50) and in
growth rate (ErC50) were estimated. It was
possible to determine No Observable Effect Concentrations (NOEC). The
results were as follows:
EC50-72h, mg/L (95% CI)
Cell growth – Biomass (b)
200 (150 – 270)
Growth rate – Cell multiplication (r)
310 (230 – 470)
CI: confidence intreval
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