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EC number: 203-308-5
CAS number: 105-55-5
The acute oral toxicity of DETU was studied in male mice. Groups of 10
-20 mice were treated with DETU by gavage. The doses used were : 500,
700, 1000, 1400, 2000, 2800 mg/kg bw. A group of 10 mice wasn't treated,
it was a control group. Animals were observed three hours after
administration for clinical signs, and five days for mortality.
No mortality and no clinical signs were observed at 0 and 500 mg/kg bw.
10/20 mice died at 700 mg/kg, and most of mice died at 1000, 1400, 2000
and 2800 mg/kg bw. Clinical signs observed in these animals were
sedation, dyspnea, whrighting, tremor, hypothermia.
According these results, the LD50 of DETU was 930 mg/kg bw in male mice.
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