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EC number: 203-782-3
CAS number: 110-60-1
1,4 Butanedamine did not demonstrate mutagenic
activity in any of the bacterial assays with or without metabolic
activation (S9) in Salmonella typhimurium TA-1535, TA-1537, TA-1538,
TA-98, TA-100, and Saccharomyces cerevisiae D4, in Eschericia coli
WP2uvrA, W3110/pol A+, P3478/pol A- and was considered not mutagenic
under these test conditions.
1,4 -Diaminobutane (67%) is also not clastogenic in
human lymphocytes under the experimental conditions described in the
report, nor in the mouse lymphoma L5178Y test system under the
experimental conditions described in these reports.
Not classified, based on the test results with 1,4 diaminobutene
of all in vitro bacterial assays, and the in vitro chromosome
abberration test in cultured peripheral human lymphocytes (with repeat experiment),
and in vitro mammalian cell gene mutation test with mouse lymphoma
cells (with independent repeat), 1,4 diaminobutane is considered not to be
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