Tetramethylenediamine

Exposure related observations in humans: other data

Administrative data

Endpoint:

exposure-related observations in humans: other data

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: not personal measurements, but results of stationary measurements on the workplace

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2008

Report date:

2008

Materials and methods

Test material

Test material information

Constituent 1

Reference substance name:

Tetramethylenediamine

EC Number:

203-782-3

EC Name:

Tetramethylenediamine

Cas Number:

110-60-1

Molecular formula:

C4H12N2

IUPAC Name:

butane-1,4-diamine

Method

Ethical approval:

not applicable

Details on study design:

During Turn Around activities at the DAB-fabriek the installation is opened up for maintenance activities.
During these maintenance activities potential exposure to1,4-di aminobutane (DAB) has been measured (local, stationary measurements in the air).

Exposure assessment:

measured

Results and discussion

Results:

All but one measurement were below the analytical detection level (0.01-0.03 mg/m3).
One measurement =0.03 mg/m3

Applicant's summary and conclusion

Conclusions:

All but one measurement were below the analytical detection level (0.01-0.03 mg/m3).
One measurement =0.03 mg/m3
These concentrations measured in areas where people work, are fare below the DNEL (7 mg/m3).

Executive summary:

During a turn around (maintenace activities) at the DAB plant, stationary measurements in air were performed.

All but one measurement were below the analytical detection level (0.01-0.03 mg/m3).

One measurement =0.03 mg/m3

These concentrations measured in areas where people work, are fare below the DNEL (7 mg/m3).