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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Classification & Labelling & PBT assessment

PBT assessment

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Administrative data

PBT assessment: overall result

PBT status:
the substance is not PBT / vPvB

Based on the readily biodegradable classification tested according to OECD 301 B test (Desmares- Koopmans, 2009) 1,4 diaminobutane is not (very) persistent , not P and vP.

The octanol/water partition coefficient (log Kow = -0,65, Source: Safety Data Sheet WorldWise v.3.02, 1 September 2006) meets the criterion of log Kow < 4,5, from which it can be concluded that 1,4 diaminobutane is not a bioaccumulating substance, not B and vB.

The only available aquatic toxicity data from a study is the 96h-LC50 value in fish of 730 mg/l (Vaessen P, Meijers J, 1984). Although this information is considered reliable with restrictions (reliability 2), this value is used in this toxicity assessment. The toxicity criterion of EC50/LC50 < 0,1 mg/l is not fulfilled (about a factor 7000 higher) therefore the substance 1,4 diaminobutane is considered not to be toxic according to the short-term aquatic toxicity.

The data on persistence, bioaccumulation and toxicity do not fulfil the screening criteria of Annex XIII of the REACH regulation (table C.1-1 and C.1-2) and should therefore be considered not to be a PBT or vPvB substance.