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Ecotoxicological information

Toxicity to soil macroorganisms except arthropods

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Administrative data

Endpoint:
toxicity to soil macroorganisms except arthropods: short-term
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
1953
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference
Reference Type:
publication
Title:
Dodecylamine and other agents active against Ascaris lumbricoides and their toxicity in mammals
Author:
Hamilton H. Anderson and George K. Hurwitz
Year:
1953
Bibliographic source:
Arch. exper. Path. u. Pharmakol., Bd. 219, S. 119-129 (1953)

Materials and methods

Principles of method if other than guideline:
Test items were tested on Ascaris lumbricoides of swine. The chemical to be tested was diluted approximately 1:1000 in 0,9% NaCl solution.
(modification of the LAMSON and BROW~ method, 1936)

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
liquid

Test substrate

Vehicle:
not specified

Test organisms

Test organisms (species):
other: Ascaris lumbricoides
Animal group:
nematods

Study design

Study type:
laboratory study
Substrate type:
not specified
Total exposure duration:
1 h

Test conditions

Test temperature:
37 C

Results and discussion

Effect concentrations
Duration:
1 h
Dose descriptor:
LC100
Effect conc.:
1 other: g/L of a 0.9% NaCl solution
Nominal / measured:
nominal
Details on results:
Allyl isothiocyanate killed all worms in 30 minutes.

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
Allyl isothiocyanate killed all worms in 30 minutes.