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Diss Factsheets
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EC number: 618-690-2 | CAS number: 90982-32-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to soil microorganisms
Administrative data
- Endpoint:
- toxicity to soil microorganisms
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 996
- Report date:
- 1996
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- The effect of the test substance on soil microflora activity was tested during a 28-day period by exposing to the recommended maximum application rate, 10X the recommended maximum application rate and a reference substance (Pentaphenate (NaPCP)) known to effect soil microflora activity.
Soil microflora activity was evaluated by three procedures:
1) determination of soil respiration in a short term test;
2) determination of nitrogen mineralization by measuring relative proportion of ammonium nitrate and nitrite in soil; and
3) determination of microbial biomass measured by CO2 production. - GLP compliance:
- no
Test material
- Reference substance name:
- ethyl 2-({[(4-chloro-6-methoxypyrimidin-2-yl)carbamoyl]amino}sulfonyl)benzoate
- EC Number:
- 618-690-2
- Cas Number:
- 90982-32-4
- Molecular formula:
- C15H15ClN4O6S
- IUPAC Name:
- ethyl 2-({[(4-chloro-6-methoxypyrimidin-2-yl)carbamoyl]amino}sulfonyl)benzoate
- Test material form:
- solid: granular
- Details on test material:
- 25% by weight
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test substrate
- Vehicle:
- yes
- Remarks:
- Deionized water
Test organisms
- Test organisms (inoculum):
- other: Microflora in soil
Study design
- Total exposure duration:
- 28 d
Test conditions
- Test temperature:
- 20 ± 2 °C
- Moisture:
- 60%
- Nominal and measured concentrations:
- 9 and 90 g a.i./ha (equivalent to 36 and 360 g/2.205x10e9 g)
- Reference substance (positive control):
- yes
- Remarks:
- Pentaphenate (NaPCP)
Results and discussion
Effect concentrations
- Key result
- Duration:
- 28 d
- Remarks on result:
- other: No significant effects observed on soil microflora activity when applied at either the recommended maximum application rate or 10X the recommended maximum application rate
Applicant's summary and conclusion
- Conclusions:
- The test results show that the test substance did not have any significant effects on soil microflora activity when applied at either the recommended maximum application rate or 10X the recommended maximum application rate during the 28 day experimental period.
- Executive summary:
The effect of the test substance on soil microflora activity was tested during a 28 day period. A test soil was exposed to the recommended maximum application rate, 10X the recommended maximum application rate and a reference substance (Pentaphenate (NaPCP)) known to effect soil microflora activity. All chemical treatments were compared to a control treatment.
Soil microflora activity was evaluated by three procedures:
1) determination of soil respiration in a short term test;
2) determination of nitrogen mineralization by measuring relative proportion of ammonium nitrate and nitrite in soil; and
3) determination of microbial biomass measured by CO2 production.
All test procedures followed the required protocol issued by the Pest Management Regulatory Agency (PMRA).
Application of the test substance to a sandy loam test soil at both the maximum application rate and 10X the maximum rate did not effect the nitrogen mineralization or respiration activity of microflora during the experimental period with only one exception. On day 14 of the experiment, nitrate concentration in soil exposed to the recommended maximum rate of application was greater than that of soils not exposed to the test substance. However, the increased nitrate concentration did not result in an increase in the total inorganic nitrogen concentration on that day.
The microbial biomass carbon content of the test soil was not effected by exposure to the test substance applied at both the recommended application rate and 10X the recommended application rate with three exceptions. On Day 0 of the experiment, microbial biomass carbon content in soil exposed to 10X the recommended maximum rate of application was lower than that of control soil. This effect was not realized on subsequent sampling days. On days 7 and 28, microbial biomass carbon content was higher in soils exposed to the test substance at the recommended application rate compared with that of control soils (p ≤0.05). This effect was not significant at p ≤0.01.
In conclusion, the test results show that the test substance did not have any significant effects on soil microflora activity when applied at either the recommended maximum application rate or 10X the recommended maximum application rate during the 28 day experimental period.
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