Registration Dossier
Registration Dossier
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EC number: 618-690-2 | CAS number: 90982-32-4
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model, but not (completely) falling into its applicability domain, with adequate and reliable documentation / justification
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- OECD Toolbox v3.1
Estimation for BOD by CATALOGIC: 301C v.10.14
Toolbox prediction report is attached in IUCLID - GLP compliance:
- no
Test material
- Reference substance name:
- ethyl 2-({[(4-chloro-6-methoxypyrimidin-2-yl)carbamoyl]amino}sulfonyl)benzoate
- EC Number:
- 618-690-2
- Cas Number:
- 90982-32-4
- Molecular formula:
- C15H15ClN4O6S
- IUPAC Name:
- ethyl 2-({[(4-chloro-6-methoxypyrimidin-2-yl)carbamoyl]amino}sulfonyl)benzoate
- Test material form:
- solid
- Details on test material:
- Purity: Assume 100%
Constituent 1
- Specific details on test material used for the study:
- Smiles: CCOC(=O)c1ccccc1S(=O)(=O)NC(=O)Nc1nc(Cl)cc(OC)n1
Results and discussion
% Degradation
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 0.21
- St. dev.:
- 0.006
- Remarks on result:
- not readily biodegradable based on QSAR/QSPR prediction
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- 0.21% degradation was predicted
- Executive summary:
The catalogic model for biodegradation was used within the QSAR Toolbox. 0.21% degradation based on BOD was predicted indicating the test substance is not readily biodegradable. Additional supporting documention is provided in the prediction report attached in IUCLID.
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