Registration Dossier
Registration Dossier
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EC number: 618-690-2 | CAS number: 90982-32-4
Particle size distribution (Granulometry)
Administrative data
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: CIPAC MT 187
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- Laser scattering/diffraction
Test material
- Reference substance name:
- ethyl 2-({[(4-chloro-6-methoxypyrimidin-2-yl)carbamoyl]amino}sulfonyl)benzoate
- EC Number:
- 618-690-2
- Cas Number:
- 90982-32-4
- Molecular formula:
- C15H15ClN4O6S
- IUPAC Name:
- ethyl 2-({[(4-chloro-6-methoxypyrimidin-2-yl)carbamoyl]amino}sulfonyl)benzoate
- Test material form:
- solid: particulate/powder
- Details on test material:
- Purity: 99.5%
Constituent 1
Results and discussion
Particle size
- Key result
- Percentile:
- other: Range
- Remarks on result:
- other: Particles were found to be in the range 0.3 to 360 μm
Any other information on results incl. tables
Mass median diameter
Volume (%): 44.9 μm
Number (%): 0.5 μm
Applicant's summary and conclusion
- Conclusions:
- Particles were found to be in the range 0.3 to 360 μm
- Executive summary:
The purpose of this study was to evaluate the particle size distribution of the test substance according to the guideline CIPAC MT 187. The size distribution of particles present in the test substance was assessed using particle size apparatus based on laser diffraction.
Test substance (100 mg) was transferred to a vial and mixed with distillate to prepare a smooth paste. The paste was then transferred to the sampling tank which was filled with light distillate as the dispersant. Two measurements were taken 20 seconds apart and the mean data was calculated. The test was performed in duplicate.
Particles were found to be in the range 0.3 to 360 μm.
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