Registration Dossier

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
0.166 mg/L
Assessment factor:
50
Extrapolation method:
assessment factor
PNEC freshwater (intermittent releases):
1.2 mg/L

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
0.017 mg/L
Assessment factor:
500
Extrapolation method:
assessment factor

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
100 mg/L
Assessment factor:
10
Extrapolation method:
assessment factor

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
0.764 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
0.076 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
0.055 mg/kg soil dw
Extrapolation method:
equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential for bioaccumulation

Additional information

Derivation of PNECs

The PNECs for the different compartment can be calculated either by applying an assessment factor (PNECfreshwater, marine water, intermittent release and STP) or using the Equilibrium Partitioning Method (PNECsediment freshwater, sediment marine water and soil). The PNECoral and PNECair are considered as not relevant. The utilized procedures are described in detail in the ECHA REACH Guidance of May 2008, Chapter R.10 ("Guidance on information requirements and chemical safety assessment").

Environmental classification and labelling

Experimental investigations were performed in order to investigate the toxicity of 1,2,3-Propanetriol, glycidyl ethers towards aquatic microorganisms, green algae and daphnids. The toxicity towards Daphnia magna was conducted with an exposure time of 21 days (long-term test). The potential of short-term toxicity to daphnids, as well as short- and long-term toxicity towards fish were predicted with the scientifically accepted QSAR tool EPIWIN (software ECOSAR v1.00 and v0.99g by US-EPA). For chemical safety assessment (CSA), the experimental results are taken more into account; however, the QSAR predictions support the experimental results for the test substance.

The toxicity experiment with the algae species Pseudokirchneriella subcapitata (OECD Guideline 201; Liedtke, 2013) revealed an ErC50(72h) > 120 mg/L, thus indicating that there is no acute hazard potential towards this organisms. The long-term exposure to Daphnia magna revealed a No Observed Effect Concentration (NOEC) of 8.3 mg/L (OECD Guideline 211; Liedtke, 2013). As supporting information, the predicted Chronic Values (ChVs, reveal the geometric mean of the LOEC and NOEC) of the three trophic levels (fish, daphnids and algae) indicates that there is no toxicity concern (Chemservice S.A., 2015c).

In a Manometric Respirometry Test, conducted in accordance with OECD Guideline 301F the test substance was found to be not readily biodegradable so that the substance is considered as persistent in the environment (please refer to PBT assessment). However, 24 % degradation were attained within 55 days exposure period. Furthermore, bioaccumulation is not expected, based on the predicted Bioconcentration Factor (BCF) of 3.16 L/kg w.w. by BCFBAFv3.01 (Chemservice S.A., 2013).

Concerning all available data and in reference to Regulation (EC) No. 1272/2008, 1,2,3-Propanetriol, glycidyl has not to be classified and labelled with respect to environmental hazards.

Conclusion on classification

In accordance to Regulation (EC) No. 1272/2008 (Classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No. 1907/2006), 1,2,3-Propanetriol, glycidyl has not to be classified and labelled with respect to environmental hazards.