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Sediment toxicity

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Description of key information

The three studies carried out on 4,4'-MDA with Lumbriculus (Egeler, 2002), Chironomus (Egeler & Gilberg, 2005) and Hyalella (Egeler & Gilberg, 2005) are all well documented and of comparable good quality.

Key value for chemical safety assessment

Additional information

The key results of the three MDA studies (Egeler, 2002; Egeler & Gilberg, 2005) were carried out with the three species representing different living and feeding conditions. All studies are deemed to be long-term and NOEC values ranging from 3.75 to 500 mg MDA/kg sediment (dry weight) were obtained. Taking the lowest value and applying the prescribed assessment factor of 10, a PNECsediment of 0.375 mg MDA/kg sediment (d.w.) may be determined.

The acetonic solutions of the test item were examined analytically. The test item concentrations were found to be in the range of the nominal concentrations.