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Ecotoxicological information

Short-term toxicity to fish

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Link to relevant study record(s)

Description of key information

The Yokohoma Laboratories study was carried out to the highest quality standards and delivered the lowest LC50 for fish.. 

Key value for chemical safety assessment

Additional information

The Yokohoma Laboratories study is highly detailed and was given a reliability of one because of compliance with GLP and inclusion of certificate. The 96h LC50 value of 20.6mg/l indicates that 4,4'-MDA has some toxicity to fish, though results elsewhere confirm that for 4,4'-MDA fish are not the most sensitive species of the three trophic levels of the base-set (fish, daphnia and algae).