Registration Dossier
Registration Dossier
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EC number: 241-034-8 | CAS number: 16961-83-4
Endpoint summary
Administrative data
Description of key information
Hexafluorosilicic acid is listed in Table 3 of Annex VI to the CLP Regulation. (in force from 1 March 2018) as "Skin Corr. 1B (H314). No additional data are available and none are required.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (corrosive)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Hexafluorosilicic acid is a strong acid that can corrode glass and stoneware (NTP: Haneke & Carson, 2001). Further testing for skin and irritation/damage was waived based on GLP Regulation Annex VII, column 2 specific rules of adaptation of 18 December 2006.
Supporting information from a non-standard histological investigation in the skin of rats, guinea-pigs and pigs also indicate a corrosive effect which may be delayed and is more marked in damaged skin (Alhassan & Zink, 1982). Human experience additionally indicates that the substance is likely to be corrosive.
Justification for classification or non-classification
Hexafluorosilicic acid is a strong acid which is classified as H314 (Causes severe skin burns and eye damage) according CLP Regulation (No. 1272/2008 of 16 December 2008).
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