Registration Dossier

Diss Factsheets

Ecotoxicological information

Toxicity to soil macroorganisms except arthropods

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
toxicity to soil macroorganisms except arthropods: long-term
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Justification for type of information:
see read across justification
Reason / purpose for cross-reference:
read-across source
GLP compliance:
no
Duration:
22 wk
Dose descriptor:
NOEC
Effect conc.:
1 200 mg/kg soil dw
Nominal / measured:
nominal
Conc. based on:
test mat.
Remarks:
F-
Basis for effect:
growth
Remarks on result:
other: fluoride
Details on results:
The NOEC for sodium fluoride is 1200 mg F-/kg dw. Applying the conversion factor from F- to hexafluorosilicic acid, the NOEC corresponds to 1512 mg hexafluorosilicic acid/kg dw.
Conclusions:
The NOEC for sodium fluoride is 1200 mg F-/kg dw. Applying the conversion factor from F- to hexafluorosilicic acid, the NOEC corresponds to 1512 mg hexafluorosilicic acid/kg dw.
Executive summary:

The toxicity of various fluoride compounds to Eisenia fetida was investigated over a period of 22 weeks. At higher concentrations sodium fluoride, potassium fluoride and the sodium salt of fluoroacetic acid reduced significantly. Calcium fluoride had no effect. The rate of maturity of the earthworms was also significantly reduced when sodium fluoride and potassium fluoride was used. The number of hatchlings was reduced in the presence of sodium fluoride, while the number of cocoons was reduced in the presence of a low concentration of sodium fluoride and potasium fluoride. No data is available on the effects of hydrogen fluoride on the growth, maturity and and fertility of the earthworm. However, in a terrestial environment the submission substance exists predominantly as fluoride ions. Therefore the results above are a good indication of the behaviour of hydrogen fluoride in the terrestial environment.

The NOEC for sodium fluoride is 1200 mg F-/kg dw. Applying the conversion factor from F- to hexafluorosilicic acid, the NOEC corresponds to 1512 mg hexafluorosilicic acid/kg dw.

Description of key information

The NOEC for sodium fluoride is 1200 mg F-/kg dw. Applying the conversion factor from F- to hexafluorosilicic acid, the NOEC corresponds to 1512 mg hexafluorosilicic acid/kg dw.

Key value for chemical safety assessment

Long-term EC10, LC10 or NOEC for soil macroorganisms:
1 512 mg/kg soil dw

Additional information

The toxicity of various fluoride compounds to Eisenia fetida was investiated over a period of 22 weeks. At higher concentrations sodium fluoride, potassium fluoride and the sodium salt of fluoroacetic acid reduced significantly. Calcium fluoride had no effect. The rate of maturity of the earthworms was also significantly reduced when sodium fluoride and potassium fluoride was used. The number of hatchlings was reduced in the presence of sodium fluoride, while the number of cocoons was reduced in the presence of a low concentration of sodium fluoride and potasium fluoride (Vogel & Ottow, 1992).

The NOEC for sodium fluoride is 1200 mg F-/kg dw. Applying the conversion factor from F- to hexafluorosilicic acid, the NOEC corresponds to 1512 mg hexafluorosilicic acid/kg dw.

Categories Display