Registration Dossier

Administrative data

Endpoint:
health surveillance data
Adequacy of study:
disregarded due to major methodological deficiencies
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Documentation insufficient for assessment

Data source

Reference
Reference Type:
publication
Title:
Prevalence of occupational asthma in spray painters exposed to several types of isocyanates, including polymethylene polyphenylisocyanate
Author:
Séguin P, Allard A, Cartier A and Malo JL
Year:
1987
Bibliographic source:
J. Occup. Med. 29, 04, 340-344

Materials and methods

Study type:
health record, other

Test material

Constituent 1
Chemical structure
Reference substance name:
3-isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate
EC Number:
223-861-6
EC Name:
3-isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate
Cas Number:
4098-71-9
Molecular formula:
C12H18N2O2
IUPAC Name:
5-isocyanato-1-(isocyanatomethyl)-1,3,3-trimethylcyclohexane

Results and discussion

Any other information on results incl. tables

RS-Freetext:
Occupational asthma was confirmed in six of the 51 subjects.

Applicant's summary and conclusion

Conclusions:
CL-Freetext:
A prevalence of 11.8 % for occupational asthma in spray
paint shops was reported.