Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Long-term toxicity to fish

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Administrative data

Link to relevant study record(s)

fish early-life stage toxicity
Data waiving:
exposure considerations
Justification for data waiving:

Description of key information

The aquatic toxicity testing: Long-term toxicity to fish has been judged to be not necessary in accordance with section 3 of REACH Annex XI. 

Key value for chemical safety assessment

Additional information

Operational conditions (OC) and risk mitigating measures (RMMs) described in the CSR define how direct or indirect exposure into the environment is prevented. It is demonstrated that emissions into the environment are effectively reduced to a negligible level of exposure for the whole lifecycle of the substance.  The risk characterization ratios indicate that Isophorone diisocyanate pose no risk for the environment and that exposure is well below effect concentrations.