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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Description of key information

The toxic effects of isophorone diisocyanate on Scenedesmus subspicatus were investigated by Bayer AG (2000) according to EU method C.3. Seven concentrations ranging from 1.1 to 70.0 mg/L were tested over a period of 72 hours. The EC50 (72 hours, growth rate) was determined as >70 mg/L and the NOEC as 4.4 mg/L.

Key value for chemical safety assessment

Additional information

In view of the low solubility in water (see chapter 4.9) and the liability towards hydrolysis (see chapter 5.1.2) of 3-isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate, exposure to well-defined aquatic concentrations is difficult to achieve. Due to fast hydrolysis, the observed effect is expected to be the effect of the hydrolysis product. In the aquatic environment, only the chemically less reactive hydrolysis product is expected to be relevant. The method for the determination of the test substance concentration (TOC) does not differentiate between parent substance and hydrolysis product. Hence the analytical results should be treated with caution.