Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 226-241-3 | CAS number: 5332-73-0
Dissociation constant
Administrative data
Link to relevant study record(s)
- Endpoint:
- dissociation constant
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 25-07-2011 - 26-07-2011
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 112 (Dissociation Constants in Water)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): MOPA, 3-methoxypropylamine
- Physical state: Liquid
- Analytical urity: 99.4% by GC
- Purity test date: 12-04-2010
- Lot/batch No.: 9M603 - Dissociating properties:
- yes
- No.:
- #1
- pKa:
- 10.4
- Temp.:
- 20 °C
- Remarks on result:
- other: No details on temperature are provided, however ambient temperature is anticipated
- Conclusions:
- The dissociation constant of the substance was determined to be 10.4 ± 0.5 at ambient temperature.
Reference
Description of key information
The dissociation constant of the test substance was determined to be 10.4 ± 0.5 at ambient temperature, following a GLP study conducted in accordance with guideline OECD 112 using the titration method (Shajad Younis, 2011).
Key value for chemical safety assessment
- pKa at 20°C:
- 10.4
Additional information
Although the temperature was not reported it was assumed that the study was conducted at ambient temperature.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
