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Water solubility

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water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
according to guideline
EU Method A.6 (Water Solubility)
GLP compliance:
yes (incl. QA statement)
Type of method:
other: Preliminary estimate
Specific details on test material used for the study:
- Name of test material (as cited in study report): MOPA, 3-methoxypropylamine
- Physical state: Liquid
- Analytical urity: 99.4% by GC
- Purity test date: 12-04-2010
- Lot/batch No.: 9M603
Key result
Remarks on result:
other: During the estimation stage of the water solubility analysis, the sample was found to have infinite solubility in water.
Details on results:
The substance was found to be completely miscible with water (testing 11.21 mg up to 24.324 g in 0.05 mL of water).
Since the estimated solubility was outside the measurement range of the analysis, the test was terminated. It is therefore concluded that MOPA has infinite solubility in water (estimated).
Temperature of measurement was not recorded; ambient conditions are anticipated.
The substance is concluded to be miscible with water in all proportions, under ambient conditions.

Description of key information

The test substance was determined to be miscible with water in all proportions under ambient conditions, in a GLP study according to the preliminary test as specified in test method EC A.6 (Shajad Younis, 2011).

Key value for chemical safety assessment

Water solubility:
100 g/L
at the temperature of:
20 °C

Additional information

The substance is miscible with water in all proportions. The bounded value of 100 g/L is used as the key value for chemical safety assessment, being the maximum value for water solubility as defined in the EUSES program.

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