Registration Dossier

Administrative data

Endpoint:
dermal absorption in vivo
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Authoritative data base
Title:
Danish QSAR study for CAS No.: 103-73-1
Author:
Danish EPA Model
Year:
2012
Bibliographic source:
QSAR predictions by Danish Environmental Protection Agency (EPA)model powered by OASIS database:-EPI Suite (DERMWIN) Various versions of EPI Suite dating back from 1990-2004.

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: Modelling Database
Principles of method if other than guideline:
Data is from Danish QSAR
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): phenetole
- Substance type: Organic
- Physical state: Liquid
Radiolabelling:
not specified

Test animals

Species:
other: no data
Strain:
not specified
Sex:
not specified

Administration / exposure

Type of coverage:
not specified
Vehicle:
not specified

Results and discussion

Percutaneous absorption
Remarks on result:
other: Dermal abs.mg/cm2/event: 0.01400 (MODERATE)

Applicant's summary and conclusion

Conclusions:
Dermal absorption value of phenetole estimated at dose concentration 0.01400 mg/cm2/event indicate MODERATE absorption
Executive summary:

Dermal absorption value of phenetole estimated at dose concentration 0.01400 mg/cm2/event indicate MODERATE absorption from Danish QSAR model.