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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Description of key information

The effective concentration (EC50) value of Phenetole in Daphnia magna in a 48 hr study on intoxication effect was estimated to be 117.0316 mg/L.

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
2.7 mg/L

Additional information

Toxicity to aquatic invertebrate

Based on predicted data of target substance(K2) and studies of readacross reviewed for short term toxicity toaquatic invertebrate from reliable sources having Klimisch rating 4 considering weight of evidence approach. The summary of the results are presented below

 

Sr.No

Endpoint

Effect values

Basis for effects

Duration

Species

Remarks

1.

EC50

117.0316 mg/L

Intoxication

48 hrs

Daphnia magna

Predicted data

2.

LC50

488 mg/L

Mortality

48 hrs

Daphnia magna

Study report(RA-122-99-6)

3.

LC50

2.7 mg/L

Mortality

48 hrs

Daphnia magna

DEPA

 

By applying weight of evidence approach the endpoint values for target was assessed as follows- EC50-117.0316 mg/L,LC 50 value of target was predicted to be 2.7 mg/l. However the data was insufficient to classify the substance in aquatic chronic category. Thus considering the weight of evidence approach for target and readacross values it was concluded that phenetole does not exhibit toxicity toaquatic invertebrate.