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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

The lethal concentration (LC50) value of Phenetole in fish [Lepomis macrochirus] in a 96 hr study on mortality effect was found to be 103.4304 mg/L . Thus,considering the CLP Criteria for aquatic classification of the substance , it is concluded that Phenetole does not exhibit short term toxicity to fish [Lepomis macrochirus].

 

Key value for chemical safety assessment

LC50 for freshwater fish:
32.95 mg/L

Additional information

Based on predicted data of target substance and studies of readacross reviewed for short term toxicity to fish  from reliable sources having Klimisch rating 2 and 4 considering weight of evidence approach. The summary of the results are presented below

Sr.No

Endpoint

Effect values

Basis for effects

Duration

Species

Remarks

1.

LC50

103.4304 mg/l

 mortality

 

96 hrs.

 

Lepomis macrochirus

 

Predicted data

2.

LC50

 100.5091mg/l

 

 mortality

 

96 hrs.

 

 Pimephales promelas

 

Predicted data

3.

LC 50

32.95 mg/l

mortality

96 hrs.

Pimephales promelas

DEPA

3.

LC50

 120 mg/l

 

mortality

48 hrs

 Leuciscus idus melanotus

 

Publication(RA-100-66-3)

4.

LC50

344 mg/l

mortality

96 hrs

Pimephales promelas

Publication(RA-122-99-6)

5.

LC50

165 mg/l

135 mg/l

mortality

24 hrs

48 hrs

Ptychocheilus oregonensis

Publication(RA-122-99-6)

 

By applying weight of evidence approach the endpoint values varies between 100.5 to 344 mg/l in a 24 to 96 hrs.study on the basis of mortality effect.The LC 50 value 32.95 mg/L is a classifying value.However the data is insufficient for classifying the substance. Thus, considering the CLP Criteria for aquatic classification of the substance and weight of evidence approach , it is concluded that Phenetole does not exhibit short term toxicity to fish (Lepomis macrochirus, Pimephales promelas, Leuciscus idus melanotus & Ptychocheilus oregonensis).