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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

Based on the reliable data from closed vessel study, after 48 hours of exposure to the test substance, a EC50 = 50.42 mg/L was calculated for Daphnia magna.

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
50.42 mg/L

Additional information

The study of de Nadai (2009) was judged as the most reliable. The report was extensively detailed and used adequate design (sealed test vessels) to ensure exposure of the test substance throughout the duration of the test. The results are deemed to be fully reliable with the exceptions that no chemical analysis were performed. At the end of the test it was calculated a 48h-EC50 = 50.42 mg/L. Another reliable study was available (Dion 1982). There is no information relative to the type (closed vs open) of vessels used to take into account the volatile potential. However, analytical monitoring was provided showing that the concentration of the test substance did not evolve during 48 hours. As a result, this data was flagged as a supporting study, giving a 24h-LC50 of 81 mg/L in Daphnia magna. In the other study (Samel 2000), there was neither indication of the type of vessel used, nor analytical information allowing to assess the maintenance of the test substance; preventing to attribute a high reliability to this data.