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EC number: 208-419-2
CAS number: 527-60-6
Phenol (TMP, Mesitol) was evaluated for its potential to produce skin
irritation and/or corrosion in a GLP compliant OECD 404 guideline study.
Three New Zealand White rabbits received a single topical application
for four hours to the intact skin under semi-occlusive conditions. All
three rabbits exhibited very slight erythema at both the 24- and 48-hour
observation periods. The irritation was resolved, with no signs of
erythema present at the 72-hour observation. No signs of edema were
observed in any of the rabbits at any observations points. The test
substance is considered a slight irritant.
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