Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 208-419-2
CAS number: 527-60-6
Phenol (TMP, Mesitol) was evaluated for its potential to produce skin
irritation and/or corrosion in a GLP compliant OECD 404 guideline study.
Three New Zealand White rabbits received a single topical application
for four hours to the intact skin under semi-occlusive conditions. All
three rabbits exhibited very slight erythema at both the 24- and 48-hour
observation periods. The irritation was resolved, with no signs of
erythema present at the 72-hour observation. No signs of edema were
observed in any of the rabbits at any observations points. The test
substance is considered a slight irritant.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again