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EC number: 259-105-7
CAS number: 54326-11-3
Clinical Observations and Mortality Data -300mg/kg
Dose Level mg/kg
Animal Number and Sex
Effects Noted After Dosing(Hours)
Effects Noted During Period After Dosing(Days)
signs of systemic toxicity
2 Individual Bodyweights and Bodyweight Changes
Animal Numberand Sex
Bodyweight (g) at Day
Bodyweight Gain (g)During Week
3 Necropsy Findings -300 mg/kg
Time of Death
Killed Day 14
No abnormalities detected
signs of systemic toxicity
Bodyweights and Bodyweight Changes -2000mg/kg
Bodyweight Gain (g) During Week
6 Individual Necropsy Findings-2000mg/kg
study was performed to assess the acute oral toxicity of the test
material in the Wistar strain rat.The
acute oral toxicity of the test item to the Wistar strain rat was
assessed in a GLP-compliant study following OECD guideline 420 (adopted
2001) and Method B1 bis Acute Toxicity (Oral) of Commission
Regulation (EC) No. 440/2008 in
a proprietary, experimental study (Harlan 2013). The study is considered
reliable and relevant for use for this endpoint.
sighting test at dose levels of 300 mg/kg bodyweight and 2000 mg/kg
bodyweight, a further group of four fasted females was given a single
oral dose of test material, as a suspension in Arachis
oil BP, at a dose level of
2000 mg/kg bodyweight. Clinical signs and bodyweight development were
monitored during the study period of 14 days. All animals were subjected
to gross necropsy.
were no deaths.
were no signs of systemic toxicity noted in the animal treated at a dose
levels of 300 mg/kg bodyweight or 2000 mg/kg bodyweight.
animals showed expected gains in bodyweight.
abnormalities were noted at necropsy.
acute oral median lethal dose (LD50) of aluminum,
benzoate C16-18-fatty acids complexes
in the female Wistar strain rat was estimated to be greater than
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