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EC number: 259-105-7
CAS number: 54326-11-3
Based on read across, the acute toxicity of (benzoato-O,O')hydroxy(octadecanoato-O,O')aluminium to Daphnia is predicted to show no effects at a water accommodated fraction nominal loading rate of 100 mg/L. Therefore, the 48 hour EL50 is determined to be > 100 mg/L (WAF).
As no data
was available for the short-term toxicity to aquatic invertebrates of (benzoato-O,O')hydroxy(octadecanoato-O,O')aluminium,
the endpoint was read across from aluminum, benzoate C16-18-fatty acids
acute toxicity of the read across substance to Daphnia was
determined in a proprietary, GLP-compliant, static limit test (Harlan
2013) following OECD guideline 202. As no effects were observed in the
preliminary range finding test, the definitive toxicity to Daphnia test
was conducted as a limit test at a nominal loading rate of 100 mg/L
alongside a blank control. Twenty Daphnia divided into four
replicates were exposed to a water accommodated fraction of aluminum,
benzoate C16-18-fatty acids complexes for
48 hours in standard ecotoxicity media adjusted to a hardness of
approximately 150 mg/L CaCO3. Observations of immobilisation
or abnormalities of behaviour or appearance of the Daphnia was
made at 24 and 48 hours and the test solution analysed for aluminium
content and total organic carbon at test initiation and termination. As
no effects were observed, the 48
hour EL50 is determined to be > 100 mg/L (WAF).
benzoate C16-18-fatty acids complexes (CAS
No. 94166-87-7, EC No. 303-385-6) is
considered suitable for read across to
(benzoato-O,O')hydroxy(octadecanoato-O,O')aluminium as it is
structurally similar being an approximate 2:1 mixture of
(benzoato-O,O')hydroxy(hexadecanoato-O,O')aluminium. The only
significant difference is the
presence of about 30% of the aluminium complex containing the saturated
C16-fatty acid, hexadecanoate, in place of the saturated C18-fatty acid,
octadecanoate. This small difference in composition is expected to have
no adverse influence on the short-term toxicity to aquatic invertebrates.
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