Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 232-140-5
CAS number: 7789-00-6
Foetotoxicity, including post-implantation losses, was observed in the
mouse following the administration of potassium dichromate in drinking
water during gestation (days 0-19). Significant developmental effects
occurred at the lowest dose level tested, 60 mg/kg bw/d (20 mg Cr(VI)/kg
bw/d) in the absence of maternal toxicity. Qualitatively similar
results were obtained in another study in which (350 mg/kg bw/d)
potassium dichromate (125 mg Cr(VI)/kg bw/d) was administered for a
shorter period, on days 6-14 of gestation. In a pregestational study in
female mice, fetotoxic effects were seen starting from the lowest dose
level tested, 250 ppm (63 mg/kg bw/d (22.1 mg Cr(VI)/kg bw/d)) potassium
dichromate. Significant levels of total chromium were found in treated
animals at sacrifice.
The results of developmental toxicity studies of various designs and
reliabilities performed in the mouse with potassium dichromate show that
this compound is a developmental toxin; similar activity is assumed for
the other compounds in this group.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Siekdami užtikrinti, kad būtų patogu naudotis mūsų svetaine, jos tinklapiuose naudojame slapukus.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again