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EC number: 232-140-5
CAS number: 7789-00-6
The results of a very large number of studies performed in vitro with
the water-soluble hexavlent chromium compounds are largely positive.
The EU RAR therefore concludes that there is a very large body of
evidence indicating that the Cr (VI) ion in solution is directly
mutagenic in in vitro systems; this conclusion is relevant to all
compounds in this group.
The EU RAR summarises the results of a number of in vitro studies of
various designs and reliability performed over a number of years. The
RAR itself also takes into account the findings of the earlier reviews
of the toxicity of Cr (VI) compounds by the UK Health & Safety Executive
(HSE, 1989) and the UK Institute of Health (IOH, 1997), which came to
similar conclusions. It is concluded that water soluble Cr (VI)
compounds are genotoxic in vitro.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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