Registration Dossier

Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2003
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
publication
Title:
OECD SIDS 1,2-DICHLOROPROPANE
Author:
OECD SIDS
Year:
2003
Bibliographic source:
UNEP PUBLICATIONS
Report Date:
2003

Materials and methods

Type of study / information:
Excretion
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
Name. 1,2-dichloropropane

Results and discussion

Applicant's summary and conclusion

Conclusions:
Urine and feces of F344 rats (4 animals/sex/concentration) were collected for 48 hours after inhalational exposure (head only) for 6 hours to 24, 235 and 470 mg [14C]1,2-dichloropropane/m3. 55 - 65 % of the recovered radioactivity was detected in urine and 6.3 - 9.7 % was detected in feces; 16 - 23 % of the radioactivity was exhaled as CO2.