Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Additional information

No functional or histopathological changes were reported in brain or nervous tissue from rats given 1,2-dichloropropane at doses up to 200 mg/kg bw/d by gavage as part of a 13-week neurotoxicity study. The substance is therefore not considered a neurotoxin agent.

Justification for classification or non-classification

Based on the reported data,the substance is not considered a neurotoxin agent.