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EC number: 201-152-2
CAS number: 78-87-5
from a GLP, OECD 429 guideline mouse local lymph node assay (Woolhiser
et al., 2003) found no stimulation of lymphocyte proliferation in
auricular lymph nodes from mice treated with up to 80%
1,2-dichloropropane, demonstrating that the substance is not a
sensitizer under the conditions of this test. This lack of allergic
potential in the mouse is consistent with structural considerations
which provide no evidence of chemical alerts (reactive groups) that
would indicate a potential to act as a sensitizer.
Based on the results of testing reported
1,2-dichloropropane has not been classified as skin sensitizer.
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