Registration Dossier
Registration Dossier
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EC number: 200-823-7 | CAS number: 74-94-2
Endpoint summary
Administrative data
Description of key information
The toxicity of dimethylamine-borane was tested according to OECD guidelines 201 and 202 for acute toxicity studies with aquatic invertebrates (Daphnia magna) and algae (Pseudokirchneriella subcapitata). No toxic effect on D. magna was observed (NOEC ≥ 100 mg/L). For P. subcapitata a 72 h ErC50 of 11.6 mg/L (95 % C.I. 10.6 – 12.6 mg/L) was determined. The 72 h NOErC is 2.2 mg/L.
Additional information
Toxicity to invertebrates:
Daphnia magna Straus was exposed for 48 hours to dimethylamine-borane in a static short-term toxicity study according to the OECD guideline 202 (2004) and in compliance with the OECD-GLP principles. The study was conducted as limit test with 100 mg/L. No effect on D. magna was observed. The nominal test concentration was confirmed analytically by ICP-OES. Therefore, the NOEC equals or is above 100 mg/L.
Toxicity to algae:
The freshwater algae Pseudokirchneriella subcapitata was exposed to dimethylamine-borane for 72 hours in a static toxicity study according to the OECD guideline 201 (2006) and in compliance with the OECD-GLP principles. In this study a 72 h ErC50 (endpoint: growth rate) of 11.6 mg/L (95 % C.I. 10.6 – 12.6 mg/L) and a 72 h NOErC (endpoint: growth rate) of 2.2 mg/L were determined. The nominal test concentrations were confirmed analytically by ICP-OES.
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