Dimethylamine-borane (1:1)

Ecotoxicological Summary

Conclusion on classification

Two study reports (rated as Klimisch 1) on aquatic organisms are available covering two trophic levels: a primary producer (freshwater algae, represented by the model species Pseudokirchneriella subcapitata) and a primary consumer (aquatic invertebrates, represented by the model species Daphnia magna).

D. magna was exposed for 48 hours to dimethylamine-borane in a static short-term GLP toxicity study (OECD 202) at a limit concentration of 100 mg/L (nominal). No effect on D. magna was observed. The nominal test concentration was confirmed analytically by ICP-OES. Therefore, the NOEC equals or is above 100 mg/L.

The freshwater algae P. subcapitata was exposed to dimethylamine-borane for 72 hours in a GLP toxicity study (OECD 201). In this study a 72 h E_rC₅₀(endpoint: growth rate) of 11.6 mg/L (95 % C.I. 10.6 – 12.6 mg/L) and a 72 h NOErC (endpoint: growth rate) of 2.2 mg/L were determined. The nominal test concentrations were confirmed analytically by ICP-OES. 

Taking into account that dimethylamine-borane is considered to be not readily biodegradable based on ThOD_NH4/ ThOD_NO3. (Hammesfahr U. 2017) and the lowest effect value was determined to be > 10 mg/L (E_rC₅₀ = 11.6 mg/L), dimethylamine-borane has to be classified as "Aquatic Chronic 3" following the provisions laid down in the CLP Regulation (Regulation (EC) No 1272/2008).